BiologicalActivity
Potentmonoamineuptakeinhibitor.Inhibitstransportersfor5-HT(SERT),dopamine(DAT)andnoradrenalin(NET)(Kivaluesare0.42,1.7and5.8nMrespectively).CentrallyactivefollowingsystemicadmiNISTrationinvivo.
CompoundLibraries
IndatralinehydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 328.67 |
| Formula | C16H15Cl2N.HCl |
| Storage | DesiccateatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 96850-13-4 |
| PubChemID | 10314472 |
| InChIKey | QICQDZXGZOVTEF-MELYUZJYSA-N |
| Smiles | ClC(C=C3)=C(Cl)C=[C@@]3[C@H]2C1=CC=CC=C1[C@H](NC)C2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 32.87 | 100 | |
| ethanol | 16.43 | 50 | |
| water | 3.29 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight328.67.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.04mL | 15.21mL | 30.43mL |
| 5mM | 0.61mL | 3.04mL | 6.09mL |
| 10mM | 0.3mL | 1.52mL | 3.04mL |
| 50mM | 0.06mL | 0.3mL | 0.61mL |
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