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Description:5-HTre-uptakeinhibitor
ChemicalName:(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenaminehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potent,orallyactiveselectiveSEROtoninre-uptakeinhibitor(SSRI);antidepressant.
LicensingInformation
SoldforresearchpurposesunderagreementfromPfizerInc.
CompoundLibraries
SertralinehydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 342.69 |
Formula | C17H17Cl2N.HCl |
Storage | DesiccateatRT |
Purity | ≥99%(HPLC) |
CASNumber | 79559-97-0 |
PubChemID | 63009 |
InChIKey | BLFQGGGGFNSJKA-XHXSRVRCSA-N |
Smiles | ClC(C(Cl)=C3)=CC=[C@@]3[C@H]2C1=CC=CC=C1[C@@H](NC)CC2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 34.26 | 100 | |
ethanol | 17.13 | 50 | |
water | 1.71 | 5 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight342.69.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.92mL | 14.59mL | 29.18mL |
5mM | 0.58mL | 2.92mL | 5.84mL |
10mM | 0.29mL | 1.46mL | 2.92mL |
50mM | 0.06mL | 0.29mL | 0.58mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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