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Tocris/TC-T 6000/5100/50/50 mg
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Tocris/TC-T 6000/5100/50/50 mg
品牌 / 
Tocris
货号 / 
5100/50
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4000-520-616
Description:Potentequilibrativenucleosidetransporter4(ENT4)inhibitor
ChemicalName:2,2'-[[4,8-Bis[bis(2-methylpropyl)amino]pyrimido[5,4-d]pyrimidine-2,6-diyl]diimino]bis-ethanol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentequilibrativenucleosidetransporter4(ENT4)inhibitor(IC50=74.4nM).Exhibits20-foldand80-foldselectivityforENT4overENT2andENT1,respectively.

TechnicalData

M.Wt504.71
FormulaC26H48N8O2
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber949467-71-4
PubChemID16757265
InChIKeyKIZLZYHFIWWKIL-UHFFFAOYSA-N
SmilesCC(C)CN(CC(C)C)C2=NC(NCCO)=NC1=C(N(CC(C)C)CC(C)C)N=C(NCCO)N=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO10.0920
ethanol10.0920

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight504.71.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.98mL9.91mL19.81mL
5mM0.4mL1.98mL3.96mL
10mM0.2mL0.99mL1.98mL
50mM0.04mL0.2mL0.4mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet