BiologicalActivity
Inhibitorofplasmamembranemonocarboxylatetransporters(MCTs)andthemitochondrialpyruvatecarrier(MPC).
LicensingInformation
SoldforresearchpurposesunderagreementfromPfizerInc.
CompoundLibraries
UK5099isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 288.3 |
| Formula | C18H12N2O2 |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 56396-35-1 |
| PubChemID | 6438504 |
| InChIKey | BIZNHCWFGNKBBZ-JLHYYAGUSA-N |
| Smiles | O=C(/C(C#N)=C/C2=CN(C3=CC=CC=C3)C1=CC=CC=C12)O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 28.83 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight288.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.47mL | 17.34mL | 34.69mL |
| 5mM | 0.69mL | 3.47mL | 6.94mL |
| 10mM | 0.35mL | 1.73mL | 3.47mL |
| 50mM | 0.07mL | 0.35mL | 0.69mL |
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