Tocris厂家直采，平行进口 Tocris Bioscience一级代理,Tocris/Valinomycin/3373/10/10 mg,转运体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Valinomycin/3373/10/10 mg

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Tocris

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3373/10

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4000-520-616

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Description:SelectiveK⁺ionophore

ChemicalName:Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveK⁺ionophore(K_0.5valuesare48,73,75,93and246mMforK⁺,Rb⁺,Cs⁺,Na⁺andLi⁺respectively)thattransportsK⁺acrossbiologicalandartificiallipidmembranes.InhibitsCa²⁺-ATPaseactivityandinducesapoptosisthroughmitochondrialmembranedepolarization,caspase-3activationandphosphatidylserinetranslocationinvitro.

TechnicalData

M.Wt	1111.32
Formula	C₅₄H₉₀N₆O₁₈
Storage	Desiccateat-20°C
CASNumber	2001-95-8
PubChemID	3000706
InChIKey	FCFNRCROJUBPLU-DNDCDFAISA-N
Smiles	O=C([C@H](C)OC([C@@H]([C@@H](C)C)NC([C@H](OC([C@@H](NC([C@@H](O1)C)=O)[C@@H](C)C)=O)[C@@H](C)C)=O)=O)N[C@@H]([C@@H](C)C)C(O[C@H]([C@@H](C)C)C(N[C@@H](C(O[C@@H](C)C(N[C@@H]([C@H](C)C)C(O[C@H]([C@@H](C)C)C(N[C@H]([C@H](C)C)C1=O)=O)=O)=O)=O)[C@H](C)C)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	27.78	25
	ethanol	27.78	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1111.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	0.9mL	4.5mL	9mL
5mM	0.18mL	0.9mL	1.8mL
10mM	0.09mL	0.45mL	0.9mL
50mM	0.02mL	0.09mL	0.18mL

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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