Tocris批发，产品货源 Tocris Bioscience一级代理,Tocris/ALX 5407 hydrochloride/1757/10/10 mg,转运体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/ALX 5407 hydrochloride/1757/10/10 mg

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Tocris/ALX 5407 hydrochloride/1757/10/10 mg

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Tocris

货号 /

1757/10

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4000-520-616

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Description:Selectivenon-transportableGlyT1inhibitor

AlternativeNames:(+)-NFPS

ChemicalName:N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycinehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivenon-transportableinhibitoroftheglycinetransporterGlyT1(IC₅₀valuesare3nMand>100μMforhumanGlyT1candGlyT2respectively).Doesnotrecognizeotherglycinesites,includingtheglycinesiteontheNMDAreceptor(IC₅₀>100μM).

LicensingInformation

SoldwiththepermissionofNPSPharmaceuticalsInc.Strictlyforinvitrouseonly

CompoundLibraries

ALX5407hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	429.92
Formula	C₂₄H₂₄FNO₃.HCl
Storage	Desiccateat+4°C
Purity	≥98%(HPLC)
CASNumber	200006-08-2
PubChemID	16078946
InChIKey	RPDGSZCYSJWQEE-GNAFDRTKSA-N
Smiles	FC(C=C2)=CC=C2[C@@H](CCN(CC(O)=O)C)OC1=CC=C(C3=CC=CC=C3)C=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	42.99	100
	ethanol	21.5	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight429.92.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.33mL	11.63mL	23.26mL
5mM	0.47mL	2.33mL	4.65mL
10mM	0.23mL	1.16mL	2.33mL
50mM	0.05mL	0.23mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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