TocrisX中国代理价格，厂家 TOCRIS 4372-10MG,Tocris/Alphaxalone/3046/50/50 mg,信号通路,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/Alphaxalone/3046/50/50 mg

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Tocris

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3046/50

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4000-520-616

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Description:DirectactivatorandpotentiatorofGABA_A

ChemicalName:(3α,5α)-3-Hydroxypregnane-11,20-dione

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AneurosteroidanestheticthatdirectlyactivatesandpotentiatesGABA_Areceptor-activatedmembranecurrent(I_GABA).Efficacybutnotpotencyisdeterminedbythealphasubunitofthereceptor(EC₅₀valuesare1.4,1.8,2.1,2.4and2.5μMforα1β1γ3,α1β1γ1,β1γ1,α2β1γ2Landα1β1γ2Lisoformsrespectively).

TechnicalData

M.Wt	332.48
Formula	C₂₁H₃₂O₃
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	23930-19-0
PubChemID	104845
InChIKey	DUHUCHOQIDJXAT-OLVMNOGESA-N
Smiles	O=[C@](C)[C@H]3CC[C@@]([C@@](C)3C4)([H])[C@]2([H])CC[C@@]1([H])C[C@H](O)CC[C@@](C)1[C@]([H])2C4=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	33.25	100
	ethanol	33.25	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight332.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.01mL	15.04mL	30.08mL
5mM	0.6mL	3.01mL	6.02mL
10mM	0.3mL	1.5mL	3.01mL
50mM	0.06mL	0.3mL	0.6mL

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