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Description:Water-solubleGABAAantagoNIST
ChemicalName:[R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinoliniumchloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Methochloridesaltof(+)-bicuculline(Cat.No.0130).Watersolubleandmorestablethanbicuculline.Non-GABAreceptor-mediatedactionsreported.
TechnicalData
M.Wt | 417.85 |
Formula | C21H20ClNO6 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 53552-05-9 |
PubChemID | 10047593 |
InChIKey | RLJKFAMYSYWMND-GRTNUQQKSA-M |
Smiles | [H][C@](C(C=CC6=C5OCO6)=C5C(O4)=O)4[C@]2([H])C1=CC3=C(OCO3)C=C1CC[N+](C)2C.[Cl-] |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
phosphatebufferedsaline | 41.78 | 100 | |
water | 41.78 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight417.85.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.39mL | 11.97mL | 23.93mL |
5mM | 0.48mL | 2.39mL | 4.79mL |
10mM | 0.24mL | 1.2mL | 2.39mL |
50mM | 0.05mL | 0.24mL | 0.48mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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