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Description:Non-peptide,potentKV1.3channelblocker
ChemicalName:N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1pentanaminehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potent,non-peptideKV1.3channelantagoNISTthatpreferentiallybindstotheC-typeinactivatedstateofthechannel(IC50~200nM).InhibitsKV1.4withanIC50of~300nM.SelectiveoverKV1.1,KV1.2,KV1.5,KV1.6,KV3.1-4,andKV4.2.
TechnicalData
M.Wt | 340.89 |
Formula | C21H24N2.HCl |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 478341-55-8 |
PubChemID | 20761468 |
InChIKey | JIRISCAPZWLWCG-UHFFFAOYSA-N |
Smiles | CCCCCN=C2C1=CC=CC=C1N(CC3=CC=CC=C3)C=C/2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto20mMinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight340.89.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.93mL | 14.67mL | 29.33mL |
5mM | 0.59mL | 2.93mL | 5.87mL |
10mM | 0.29mL | 1.47mL | 2.93mL |
50mM | 0.06mL | 0.29mL | 0.59mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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