Tocris经销商/代理商 Tocris Bioscience产品促销,Tocris/Exemestane/3759/50/50 mg,信号通路,细胞研究,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/Exemestane/3759/50/50 mg

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Tocris

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3759/50

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4000-520-616

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Description:Steroidalaromatase(CYP19)inhibitor

AlternativeNames:FCE24304,EXE

ChemicalName:6-Methyleneandrosta-1,4-diene-3,17-dione

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

IrreversIBLesteroidalaromataseinhibitor(IC₅₀=20nM).DestABIlizesaromataseandlowersestrogenlevels;orallyactive.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

CompoundLibraries

ExemestaneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	296.4
Formula	C₂₀H₂₄O₂
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	107868-30-4
PubChemID	60198
InChIKey	BFYIZQONLCFLEV-DAELLWKTSA-N
Smiles	C[C@@]12C(C(C[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CCC4=O)=C)=CC(C=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	29.64	100
	ethanol	22.23	75

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight296.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.37mL	16.87mL	33.74mL
5mM	0.67mL	3.37mL	6.75mL
10mM	0.34mL	1.69mL	3.37mL
50mM	0.07mL	0.34mL	0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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