BiologicalActivity
Reactivatorofmutantp53.Restoreswildtypep53structureandfunctiontothep53R175mutant.Inhibitsgrowthoffibroblastsexpressingthep53R175mutation(IC50=8nM).Alsoinhibitsgrowthofxenografttumorsexpressingthep53R175mutationinvivo.
CompoundLibraries
NSC319726isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 234.32 |
| Formula | C11H14N4S |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 71555-25-4 |
| PubChemID | 5351307 |
| InChIKey | XDHBUMNIQRLHGO-UKTHLTGXSA-N |
| Smiles | C/C(C1=NC=CC=C1)=NNC(N2CCC2)=S |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 23.43 | 100 | |
| ethanol | 2.34 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight234.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.27mL | 21.34mL | 42.68mL |
| 5mM | 0.85mL | 4.27mL | 8.54mL |
| 10mM | 0.43mL | 2.13mL | 4.27mL |
| 50mM | 0.09mL | 0.43mL | 0.85mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。