Tocris授权代理商，正品 TOCRIS 4372-10MG,Tocris/PF 4981517/4252/10/10 mg,信号通路,细胞研究,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/PF 4981517/4252/10/10 mg

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Tocris

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4252/10

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4000-520-616

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Description:SelectiveCYP3A4inhibitor

ChemicalName:(1-Methyl-3-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine)

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveinhibitorofCYP3A4(IC₅₀valuesare0.03,17and70μMforCYP3A4,CYP3A5andCYP3A7respectively).

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt	456.59
Formula	C₂₆H₃₂N₈
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1390637-82-7
PubChemID	71315139
InChIKey	WDWIMDKOXZZYHH-FQEVSTJZSA-N
Smiles	CN1N=C(C5=C(C6=CC=C(C)C=C6)N(C)N=C5)C2=C1N=CN=C2N3C[C@@H](N4CCCCC4)CC3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	45.66	100
	ethanol	9.13	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight456.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.19mL	10.95mL	21.9mL
5mM	0.44mL	2.19mL	4.38mL
10mM	0.22mL	1.1mL	2.19mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

PreparingStockSolutions

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