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Description:Blockssodiumandpotassiumchannels
ChemicalName:(S)-(6-Methoxyquinolin-4-yl)((2R,4S,8R)-8-vinylquinuclidin-2-yl)methanolhydrochloride
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
ClassIAantiarrythmic;reducesbothNa+andK+channelcurrents,includingINa,IKrandIKs.ProlongsQTandinducestorsadedepointes(TdP).
TechnicalData
M.Wt | 324.42 |
Formula | C20H24N2O2 |
Storage | Storeat-20°C |
CASNumber | 56-54-2 |
PubChemID | 3036746 |
InChIKey | LOUPRKONTZGTKE-LHFMAAMQSA-N |
Smiles | O[C@H](C3N(CC4C=C)CCC4C3)C2=CC=NC1=CC=C(OC)C=C12 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 32.44 | 100 | |
ethanol | 8.11 | 25 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight324.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.08mL | 15.41mL | 30.82mL |
5mM | 0.62mL | 3.08mL | 6.16mL |
10mM | 0.31mL | 1.54mL | 3.08mL |
50mM | 0.06mL | 0.31mL | 0.62mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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