BiologicalActivity
CytochromeP450inhibitor.Inhibitssynthesisoftheeicosanoid20-hydroxyeicosatetraenoicacid(20-HETE).Reducesintimalhyperplasiaandvascularremodelingfollowingendothelialinjuryinratcarotidarteries.
TechnicalData
| M.Wt | 134.14 |
| Formula | C6H6N4 |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 1614-12-6 |
| PubChemID | 1367 |
| InChIKey | JCXKHYLLVKZPKE-UHFFFAOYSA-N |
| Smiles | NN2C1=CC=CC=C1N=N2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 13.41 | 100 | |
| ethanol | 13.41 | 100 | |
| water | 13.41 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight134.14.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 7.45mL | 37.27mL | 74.55mL |
| 5mM | 1.49mL | 7.45mL | 14.91mL |
| 10mM | 0.75mL | 3.73mL | 7.45mL |
| 50mM | 0.15mL | 0.75mL | 1.49mL |
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