
ProductName | Cat# | Clone# | Isotype | Applications | Reactivity | Unit/Size |
Di-Methyl-HistoneH3(Lys79)MonoclonalAntibody | E-AB-22068 | 1F6 | IgG | WB* | Human,Mouse,Rat | 20μL,60μL,120μL,200μL |
Description
Corecomponentofnucleosome.NucleosomeswrapandcompactDNAintochromatin,limitingDNAaccessibilitytothecellularmachinerieswhichrequireDNAasatemplate.Histonestherebyplayacentralroleintranscriptionregulation,DNArepair,DNAreplicationandchromosomalstABIlity.DNAaccessibilityisregulatedviaacomplexsetofpost-translationalmodificationsofhistones,alsocalledhistonecode,andnucleosomeremodeling.
SpecSheetE-AB-22068(PDFFile)
Synonyms | HIST1H3A,H3FA,HIST1H3B,H3FL,HIST1H3C,H3FC,HIST1H3D,H3FB,HIST1H3E,H3FD,HIST1H3F,H3FI,HIST1H3G,H3FH,HIST1H3H,H3FK,HIST1H3I,H3FF,HIST1H3J,H3FJ,HistoneH3.1,HistoneH3/a,HistoneH3/b,HistoneH3/c,HistoneH3/d,HistoneH3/f,HistoneH3/h,HistoneH3/i,HistoneH3/j,HistoneH3/k,HistoneH3/l,HIST2H3A,HIST2H3C,H3F2,H3FM,HIST2H3D,HistoneH3.2,HistoneH3/m,HistoneH3/o,H3F3A,H3.3A,H3F3,PP781,H3F3B,H3.3B,HistoneH3.3 |
Swiss-Prot | P68431 |
Concentration | 1mg/mL |
Host | Mouse |
Immunogen | SyntheticPeptide |
PurificationMethod | Affinitypurification |
Formulation | PBSwith0.02%sodiumazide,50%glycerol,PH7.4 |
Storage | Storeat-20?.Avoidfreeze/thawcycles. |
Dilution | WB1:500-1:2000 |
Cautionmustbetakentoavoidcontactwithskinoreyes.Insuchacase,rinsethoroughlyatoncewithwater.Donotingest,inhale,orswallow.Seekmedicalattentionimmediately.Wearappropriateprotectiveclothingsuchaslaboratoryoveralls,safetyglassesandgloves.Itisstronglyadvisedthatthisproductshouldbehandledbypeoplewhohavebeenwelltrainedinlaboratorytechniquesandthatitishandledwithcarepursuanttotheprinciplesofgoodlaboratorypractice.Allchemicalsaredeemedpotentiallyharmful.Thevialispronetofallover.Usecaution,especiallywhenthelidisoff.
FORRESEARCHUSEONLY,NOTFORUSEINDIAGNOSTICPROCEDURES.
*RemarkIcon:
WB=WesternBlotting,IP=Immunoprecipitation,IF=Immunofluorescence,IHC=Immunohistochemistory,IHC-p=ImmunohistochemistoryParaffin,FCM=FlowCytometry,CH=ChIPAssay
Manufacturedby:Elabscience
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