Tocris/VUF 11222/5668/50/50 mg
Biological Activity
High affinity non-peptide CXCR3 agonist (pKi = 7.2).
Technical Data
| M. Wt | 552.33 |
| Formula | C25H31BrIN |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1414376-84-3 |
| PubChem ID | 71459294 |
| InChI Key | IXXWHYDKYNWDKJ-IUQUCOCYSA-M |
| Smiles | C[N+](CC1=CC=C(C2=CC=CC=C2Br)C=C1)(C)CC3=CC[C@H]4C[C@@H]3C(C)4C.[I-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| DMSO | 55.23 | 100 |
| ethanol | 5.52 | 10mM with gentle warming |
Preparing Stock Solutions
The following data is based on the product molecular weight 552.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 1 mM | 1.81 mL | 9.05 mL | 18.11 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
| 10 mM | 0.18 mL | 0.91 mL | 1.81 mL |
| 50 mM | 0.04 mL | 0.18 mL | 0.36 mL |
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Certificate of Analysis / Product Datasheet Safety Datasheet Select another language: English German French Spanish View SDSReferences
References are publications that support the products\' biological activity.
Wijtmans et al (2012) Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands. J.Med.Chem. 55 10572 PMID: 23150943
Keywords: VUF 11222, supplier, High, affinity, non-peptide, CXCR3, agonists, Chemokine, CXC, Receptors, Chemokine, CXC, Receptors, Tocris Bioscience
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