Phorbol 12,13-dibutyrate Supplier | CAS 37558-16-0 | PDBu | Tocris Bioscience
Protein kinase C activator. Induces contraction of vascular smooth muscle and inhibits MLC phosphatase (MLCP) in vascular smooth muscle. Activity does not alter intracellular Ca2+ concentration. Also inhibits the activity of Na+,K+ ATPase in OK cells.
OCC1=C[C@]([C@@](C(C)4C)([H])[C@@]4(OC(CCC)=O)[C@H](OC(CCC)=O)[C@H]3C)([H])[C@@]3(O)[C@@](C=C(C)C2=O)([H])[C@]2(O)C1上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
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以下数据基于产品分子量 504.61。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions. Molarity Calculator Calculate the mass, volume, or concentration required for a solution.*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).
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关键词: Phorbol 12,13-dibutyrate, Phorbol 12,13-dibutyrate supplier, PDBu, protein, kinases, c, pkc, activators, phorbol, esters, Protein, Kinase, C, Enzyme, Substrates, /, Activators, 4153, Tocris Bioscience
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Guinea pig ventricular cardiomyocytes were patched and superfused with Saxagliptin (2 µM, 5 min) followed by Phorbol 12,13-dibutyrate (PDB, 10 nM, 5 min) and action potentials were stimulated at a 1 Hz frequency. Action potential duration (APD) were analysed at 20%, 50% and 90% repolarization (shown in Image). PDB reduced saxagliptin-induced APD prolongation.
Phorbol 12,13-dibutyrate 实验方案以下实验方案包含使用 Phorbol 12,13-dibutyrate（目录编号 4153）的更多信息。
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Cat. No. 7050 Dual cdk4/cdk6 inhibitor; orally bioavailableBio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.Bio-TechneWHERE SCIENCE INTERSECTS INNOVATIONTM
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