VEGF血管内皮细胞生长因子

C31H32N6O2
分子量:520.6CAS Number483367-10-8纯度:≥98% 贮存条件:产品应保存在-20 °C. 参考文献:Wu, X., Walker, J., Zhang, J., Ding, S., & Schultz, P. G. (2004)。 Purmorphamine 通过激活 hedgehog 信号通路诱导成骨。 Chemistry & biology,11(9), 1229-1238。
Beloti, M. M., Bellesini, L. S., & Rosa, A. L. (2005)。 Purmorphamine 增强骨髓间充质细胞来源的人成骨细胞的成骨活性。Cell biology international,29(7), 537-541。
Oliveira, F. S., Bellesini, L. S., Defino, H. L. A., da Silva Herrero, C. F.、Beloti、M. M. 和 Rosa, A. L. (2012)。 Hedgehog信号和成骨细胞基因表达受人间充质干细胞中purmorphamine的调控。细胞生物化学杂志,113(1), 204-208。
CUR-61414 添加至愿望清单 下载 TDS 通过电子邮件发送给朋友 MSDS 目录号:3343668 说明 CUR-61414 是刺猬信号通路中 SMO(平滑)的有效拮抗剂。 Smoothened 可作为致癌基因发挥作用,据报道 CUR-61414 可阻止癌细胞增殖并诱导癌细胞凋亡。C31H42N4O5
分子量:550.7CAS Number334998-36-6纯度:≥98%储存条件:产品应保存在-20°C。参考文献:Williams, J. A. (2003)。 Hedgehog 信号通路作为 ba 治疗干预的靶标sal cell carcinoma.Drug News Perspect,16(10), 657-662。
Rubin, L. L., & de Sauvage, F. J. (2006)。 Targeting the Hedgehog pathway in cancer.Nature reviews Drug discovery,5(12), 1026-1033。
Stanton, B. Z., & Peng, L. F. (2010)。 Sonic Hedgehog 信号通路的小分子调节剂。Molecular BioSystems,6(1), 44-54.
登录或创建帐户\" aria-level=\"2\">新客户创建帐户有很多好处:结帐速度更快、保留多个地址、跟踪订单等等。
创建帐户Rho 激酶/ROCK 通路ROCK Pathway\" class=\"image\"> Rho 相关蛋白激酶 (ROCK) 通过作用于细胞骨架参与调节细胞的形状和运动。它的抑制增强了经历解离诱导的细胞凋亡的干细胞的存活。按 显示每页 8 15 30 按位置排序产品名称价格蛋白质交叉反应性 CloneSet 降序方向产品名称Cat。 No.CloneApplicationsSizePriceQtyThiazovivin1227180FA Y-27632 Dihydrochloride1293823FA Filter by 显示 8 15 30per pageSort By Position Product Name Price Protein Cross Reactivity CloneSet Descending Direction Shop ByNow Shopping by Applications Functional AssayRemove This Item Clear All 窄搜索研究兴趣干细胞研究Rho 激酶/ROCK 通路ROCK Pathway\" class=\"image\"> Rho 相关蛋白激酶 (ROCK) 通过作用于细胞骨架参与调节细胞的形状和运动。它的抑制增强了经历解离诱导的细胞凋亡的干细胞的存活。按 显示每页 8 15 30 按位置排序产品名称价格蛋白质交叉反应性 CloneSet 降序方向产品名称Cat。 No.CloneApplicationsSizePriceQtyThiazovivin1227180FA Y-27632 Dihydrochloride1293823FA Filter by 显示 8 15 30per pageSort By Position Product Name Price Protein Cross Reactivity CloneSet Descending Direction Shop By现在按研究兴趣购物 Stem Cell Research删除该项目全部清除Narrow Search Applications Functional Assay登录或创建帐户\" aria-level=\"2\">新客户创建帐户有很多好处:结帐速度更快、保留多个地址、跟踪订单等等。
创建帐户CD 437 添加到愿望清单 下载 TDS 通过电子邮件发送给朋友 MSDS 目录号:1256011 说明 CD 437 是一种合成类视黄醇,可作为视黄酸受体的选择性激动剂。据报道可在多种癌症细胞系中诱导细胞凋亡并阻止细胞周期活动。
C27H26O3
分子量:398.5CAS号125316-60-1纯度:≥95%储存条件:产品应保存在 -20°C。参考文献:Sun, S. Y., Yue, P., & Lotan, R. (2000)。多种机制在细胞凋亡中的意义由人类前列腺癌细胞中的合成类视黄醇 CD437 诱导。Oncogene,19(39), 4513-4522。
Li, Y., Lin, B., Agadir, A., Liu, R., Dawson, M. I., Reed, J. C., ... & Zhang, X. K. (1998)。 AHPN (CD437) 诱导的人肺癌细胞系生长停滞和凋亡的分子决定因素。分子和细胞生物学,18(8), 4719-4731。
Wang, W., Yang, J. , Liu, H., Lu, D., Chen, X., Zenonos, Z., ... & Liu, P. (2011)。视黄酸受体γ和肝受体同系物1对体细胞快速高效重编程为诱导性多能干细胞.美国国家科学院院刊,108(45), 18283-18288.
Recombinant Human VEGF165Synonyms: Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor,
Glioma-derived endothelial cell mitogen
Description: VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and
survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in
vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial
evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes.
VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the
murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human
VEGF is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide
chains.
Catalog #: 100-20 Lot #: 030310
Source: E.coli
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses
Endotoxin level: Endotoxin level is less than 0.1 ng per mg (1EU/mg).
Formulation: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of
0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and
stored at 4oC for 1 week or -20oC for future use.
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best
stored at -20oC. Reconstituted VEGF should be stored in working aliquots at -
20oC.
Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human
umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0
ng/ml.
For a list of references using this product please visit our website at www.peprotech.com
Usage: For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Country of Origin: USA
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