GCP2(CXCL6)单核细胞趋化蛋白1(Granulolcyte chemoattractant protein1)
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创建帐户Kartogenin 添加至愿望清单 下载 TDS 通过电子邮件发送给朋友 MSDS 目录号:4723153 描述 Kartogenin 与细丝蛋白 A(一种肌动蛋白结合蛋白)结合,并抑制其与核心结合因子 Beta 的相互作用。据报道,这种相互作用可诱导软骨分化并有效诱导人间充质干细胞转变为软骨细胞。
C20H15NO3
分子量:317.3CAS Number4727-31-5纯度:≥98%贮存条件:产品应保存在-20°C。参考文献:Marini, J. C., & Forlino, A. (2012)。从内源性干细胞中补充软骨ls.New England Journal of Medicine,366(26), 2522-2524。
Hayek, A.、Kerstetter-Fogle, A. E.、Sachlos, E. 和 Bollenbach, T. (2012)。 Kartogenin:再生医学的游戏规则改变者。再生医学,(7),475。
Ray, K. (2012)。疗法:组织工程:在软骨修复中利用干细胞。Nature Reviews Rheumatology,8(6), 308-308。
登录或创建帐户\" aria-level=\"2\">新客户创建帐户有很多好处:结帐速度更快、保留多个地址、跟踪订单等等。
创建帐户登录或创建帐户\" aria-level=\"2\">新客户创建帐户有很多好处:结帐速度更快、保留多个地址、跟踪订单等等。
创建帐户Hydroxyurea 添加到愿望清单 下载 TDS 通过电子邮件发送给朋友 MSDS 目录号:1270717 描述 Hydroxyurea 是一种单羟基取代的尿素抗代谢物,通过抑制 DNA 复制和细胞增殖表现出抗肿瘤特性。它使核糖核苷酸还原酶失活并诱导 S 期细胞周期停滞。据报道,羟基脲可降低白细胞粘附,抑制人肺癌细胞的增殖。
CH4N2O2 分子量:76.1CAS 编号 127-07-1 纯度:≥95% 储存条件:产品应保持在 -20°C。参考文献:
Yarbro, J. W.(1992 年 6 月)。氢化物的作用机制氧脲。 InSeminars in oncology(第 19 卷,第 3 号增刊 9,第 1-10 页)。
Young, C. W., & Hodas, S. (1964)。羟基脲:对 DNA 代谢的抑制作用。Science,146(3648), 1172-1174。
Elford, H. L. (1968)。羟基脲对核糖核苷酸还原酶的影响。
Cdk4 Inhibitor 添加至愿望清单 下载 TDS 通过电子邮件发送给朋友 MSDS 目录号:5466072 说明 Cdk4 Inhibitor 是一种吲哚并咔唑,是细胞周期蛋白 D1/Cdk4 的有效抑制剂。它诱导 G1 细胞周期停滞并抑制 HCT-116 和 NCI-H460 细胞中的 pRb 磷酸化。
创建帐户有很多好处:结帐速度更快、保留多个地址、跟踪订单等等。
创建帐户Product InformationRecombinant Human GCP-2
Synonyms: CXCL6
Description: GCP-2 is a connective tissue derived CXC chemokine that can signal through the
CXCR1 and CXCR2 receptors. GCP-2 selectively attracts neutrophils and has also been shown to exert
anti-angiogenic activity. Human GCP-2 is cross-react on murine cells. Recombinant human GCP-2 is a
7.9 kDa protein containing 72 amino acid residues.
Source: E.coli
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses
Endotoxin level: Endotoxin level is less than 0.1 ng per mg (1EU/mg).
Formulation: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of
0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and
stored at 4oC for 1 week or -20oC for future use.
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best
stored at -20oC. Reconstituted GCP-2 should be stored in working aliquots at -
20oC.
Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration
range of 10.0-50.0 ng/ml.
For a list of references using this product please visit our website at www.peprotech.com
Usage: For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Country of Origin: USA
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