请使用支持JavaScript的浏览器! Human CD46 Protein-蚂蚁淘商城
新闻动态

Human CD46 Protein

  
  2025-06-15
  
货号: CD6-H5226-1mg
供应商: ACROBiosystems
数量: In Stock
英文名: Human CD46 Protein
规格: 1mg
内毒素:Less than 1.0 EU per μg by the LAL method. 纯度:>95% as determined by SDS-PAGE. 活性: 产品背景:Complement regulatory protein CD46 is also known as membrane Cofactor Protein (MCP), is a type I membrane protein and is a regulatory part of the complement system. CD46 is expressed by all cells except erythrocytes. MCP acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue, and also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. In T-cells by binding to CD46, A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype. Defects in CD46 are a cause of susceptibility to hemolytic uremic syndrome atypical type 2 (AHUS2). 产品描述:Human CD46, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 33.6 kDa. The predicted N-terminus is Cys 35. The reducing (R) protein migrates as 55-60 kDa in SDS-PAGE due to glycosylation. 温馨提示:不可用于临床治疗。

本文链接: https://www.ebiomall.cn/b634-acrobio/info-1544693521.html

免责声明 本文仅代表作者个人观点,与本网无关。其创作性以及文中陈述文字和内容未经本站证实,对本文以及其中全部或者部分内容、文字的真实性、完整性、及时性本站不做任何保证或承诺,请读者仅作参考,并请自行核实相关内容。
版权声明 未经蚂蚁淘授权不得转载、摘编或利用其他方式使用上述作品。已经经本网授权使用作品的,应该授权范围内使用,并注明“来源:蚂蚁淘”。违反上述声明者,本网将追究其相关法律责任。
没有了