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Description:Antitumorandanti-HIVagent;activatesNF-κB.AlsoTGR5agoNIST
ChemicalName:(+)-(3β)-3-Hydroxylup-20(29)-en-28-oicacid
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Naturaltriterpenoidthatdisplaysanti-HIVandantitumoractivity.Inducestheproductionofreactiveoxygenspecies(ROS)andactivatesNF-κB.AlsoaGPBAreceptorpartialagonist(EC50=1.04μM,efficacy83%).
CompoundLibraries
BetulinicacidisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 456.7 |
Formula | C30H48O3 |
Storage | Storeat+4°C |
CASNumber | 472-15-1 |
PubChemID | 64971 |
InChIKey | QGJZLNKBHJESQX-FZFNOLFKSA-N |
Smiles | O[C@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@@]([H])2CC[C@@]4([H])[C@](C)3CC[C@]5([C@](O)=O)[C@@]([H])4[C@H]([C@@](C)=C)CC5)([H])C(C)1C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 22.84 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight456.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.19mL | 10.95mL | 21.9mL |
5mM | 0.44mL | 2.19mL | 4.38mL |
10mM | 0.22mL | 1.09mL | 2.19mL |
50mM | 0.04mL | 0.22mL | 0.44mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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