Human CD105 (endoglin) is a homodimeric membrane glycoprotein (1) virtually restricted to endothelial cells, and present on some leukemia cells and minor subsets of bone marrow cells. CD105 binds to TGF-b1 and b3 with high affinity (4).
Isotype: Murine IgG1 kappa
Immunogen: Membrane preparation of human B-lineage leukemia cells
Specificity: Antibody SN6 recognizes an extracellular epitope of the human CD105 homodimer with a molecular weight of about 160 kd. It has been reported to cross react with non human Primate as well as Equine and Porcine(11) CD105.
Functional Application: Antibody SN6 will augment binding of TGF-b1 to CD105 expressing leukemia cells. Antibody SN6 has been used to identify mesenchymal progenitor cells populations (8,9,10).
References:
1. Y. Haruta & B.K. Seon, (1986) Proc Natl Acad Sci USA 83: 7898-7902.
2. H. Hara, et al, (1988) Cancer Res 48: 4673-4680.
3. W.C. Biddle, et al, (1989) Leukemia Res 13: 699-707.
4. S. Cheifetz, et al, (1992) J Biol Chem 267: 19027-19030.
5. B.K. Seon, et al, (1995) Proc Am Assoc Can Res 36: 23.
6. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1756-1761, 1762-1764.
7. B.K. Seon, et al, (1996) Tissue Antigens 48: 417.
8. S Alsalameh, M Lotz, et al. (2004) Arthritis & Rhematism 50(5): 1522-1532.
9. A Banas, T Ochiya, et al. (2007) Hepatology 46: 219-228.
10. R Williams, HE McCathy, et al. (2010) PLoS ONE 5(10): e13246 doi:10.1371.
11. G Vilahur, L Badimon, et al. Oct 13, 2014 Toxicol Pathol pii: 0192623314551971.
12. M Vigano, de Girolamo, et al. (Feb 2017) J Exp Orthopaedics 4: 8.
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这样的回答可能没分,好和不好都是比较出来的,一群国产的放在一起比总有个性能比较均衡,比较突出性价比好的,
还是没有和说那个厂家的好桂林的呢好像是优利特这个厂家在做,特康的前身呢就是百特,现在的百特呢基本上是在做试剂,这些东西呢。
也搜索的到的,不过答案还是比较接近的,但想知道的是国产那个厂家生产的比较好,而只回答了一半就和介绍了下国产的血球分析仪有那个几个大的厂家,没有和区分那个最好那个第二那个次点,或许一堆鸡蛋里实在挑不出骨头。
具所知呢迈瑞的好点特康实力没有迈瑞好,迈瑞吸引了一批外资在搞研发,桂林的呢好像有个优利特现在出血分析仪,他做的尿分析仪市场的占有还可以,血的反应不是很强烈。
实在是想找个内行的给比较下。
以前用countstar,一块计数板5个孔,后来实验室又换了biorad的TC20,一块板子两个孔,只能计两个数,一盒板子30片500块,价格越来越贵。这样我一个12孔板计个数就要花百来块钱啊。大家都是这么用的?板子是塑料的,有没有什么可以清洗之后重复利用的方法?

