Description
This unique line of thiols offers a range of truly exciting surface immobilization schemes. The EG linker makes these compounds suitable for inclusion in mixed SAMs resisting nonspecific absorption (with simple EGn thiols as the background; cf. cat # TH000 - TH005), and the azide group provides a biospecific handle for Sharpless "click" chemistry. (Angew. Chem. Int. Ed. 41, 2596, 2002) towards acetylene-bearing reagents.It has been recently been shown that the click chemistry can be used to immobilize various (bio)molecules chemoselectively and in excellent yields (J. Am. Chem. Soc. 127, 8600, 2005), and that it can be coupled with electrochemistry to allow for site-selective immobilization (J. Am. Chem. Soc. 128, 1794-1795, 2006 and also Science, Editor's Choice, 10 February, 2006). In the latter case, application of voltage bias to a gold microelectrode supporting azide-terminated SAM changed the redox state of an auxiliary copper catalyst, and thus activated the SAM for the "click" chemistry. By activating different microelectrodes at different times, it was possible to immobilize various molecules onto them. The capability of such sequential immobilization should prove extremely useful in the development of electrochemical microsensor arrays.
Note: Please see our related product Cat. FT 010-m11 (under Functionalized Thiols) and also silane analogs for functionalization of glass, Si and PDMS (under Silanes).
ProChimia
波兰ProChimia成立于2001年。专注于化学领域,纳米技术和生物技术领域,ProChimia为化学和生化各种类型的表面和材料的改性提供了一流的解决方案。产品用于官能化自组装单分子膜的化学物质,以及单分散金属(金、银、铜、铂、钯)和氧化铁纳米粒子功能化与各种配体。产品被全球2000多组织采用,客户包括著名学术机构(哈佛大学、麻省理工学院、斯坦福、伯克利、牛津、ETH等)以及领先的高科技公司(Intel、Fuji、IBM、Qiagene,等等)。
PROCHIMIA,公司是一家成立於经销商,年並從事2005行業的,进出口—化学和制药公司.它同時從事 ProchimiaSurfaces授权代理进口代理全国代理一级代理 苏州蚂蚁淘-代理销售波兰ProchimiaSurfaces公司的产品 ProchimiaSurfaces Acetyl-protectedthiols(乙酰保护硫醇)Calixarenes(杯芳烃)Couplingreagents(偶联试剂)Disulfides(二硫化物)Dithiolsfornanoparticleassembly(纳米颗粒组装用二硫醇)Fluorinatedthiolsandsilanes(氟化硫醇和硅烷)Functionalizedthiols(功能化硫醇)Graphenederivatives(石墨烯衍生物)Ligandsforironoxidesurfaces(氧化铁表面配体)MOFs(Metal-OrganicFrameworks,金属有机框架化合物)Photoswitchablethiols(光开关硫醇)Silanes(硅烷)ThiolatedCarbohydrates(mimickingglycans)(硫代碳水化合物-模拟聚糖)Thiolatedcrownethers(硫化冠醚)ThiolsanddisulfidesforfluorescentSAMs(用于荧光SAMs的硫醇和二硫化物)ThiolsforbioresistantandbiospecificSAMs(用于生物抗药性和生物特异性SAMs的硫醇)ThiolsforelectroactiveSAMs(用于电活性SAMs的硫醇)Thiophoshonates(硫代磷酸酯)Ultra-bioresistantZwitterionicligands(超生物电阻两性离子配体)Usefulsyntheticprecursorsandbuildingblocks(有用的合成前体和组成链段)
Prochimia公司将产品的高质量作为最高标准,每一个产品都要通过严格的质量监测体系检测,确保了稳定可靠的产品。目标是提供卓越的产品和高效的技术支持,同时还努力开发更先进的检测系统,保证客户能得到代表最高水平的服务。
从研究与临床需要出发,设计开发产品,真正满足实际要求,产品已被生命科学研究群体所广泛认同;有完善的专业文献资料积累,所有产品都提供详细的技术资料与重要的相关文献;产品提供多种规格,可以适应各种不同要求,此外还可根据实验要求选择特定的产品形式或规格。
波兰ProChimia成立于2001年。专注于化学领域、纳米技术和生物技术领域,ProChimia为化学和生化各种类型的表面和材料的改性提供了一流的解决方案。产品用于官能化自组装单分子膜的化学物质,以及单分散金属(金、银、铜、铂、钯)和氧化铁纳米粒子功能化与各种配体。产品被全球2000多组织采用,客户包括著名学术机构(哈佛大学、麻省理工学院、斯坦福、伯克利、牛津、ETH等)以及领先的高科技公司(Intel、Fuji、IBM、Qiagene等等)。
Superiorchemicalsforselfassembly,surfacemodificationandnanoparticles.
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Author:AndrewJ.Hall,MilenaQuaglia,PanagiotisManesiotis,ErsiliaDeLorenzi,andBörjeSellergren
Resource:AnalyticalChemistry,2006,78(24):8362-8367.
Abstract:
Arangeof2-acrylamidopyridines,showingsubtledifferencesinsolutionbindingtowardcarboxylicacids,hasbeeninvestigatedasfunctionalmonomersinmolecularimprinting.ImprintingofN-Z-L-glutamicacidwithonesuchmonomerisshowntobeeffectiveinthecreationofamolecularlyimprintedpolymer(MIP)withrecognitionpropertiesforitstemplateandalsoforlargermoleculescontainingglutamicacidresidues.IncomparisontoaMIPpreparedviaamore"trADItional"approach,thenewpolymericreceptorsexhibitreducednonspecificbinding.Thenewreceptorsarecomparedwithpreviouslyreportedurea-basedreceptorstargetingtheglutamicacidresidueandreceptorstargetingthepteridinesubstructureoffolicacid.
PMID:17165828
苏州高分子科学先进材料有限公司
polymer英[ˈpɒlɪmə(r)]美[ˈpɑ:lɪmə(r)]
n.多聚物; [高分子] 聚合物;
[例句]The nature of the polymer is currently a trade secret.
这一聚合物的性质目前是个商业机密。
[其他]复数:polymers
免疫组化多聚物法
immunohistochemistry
英[ɪmjʊnəʊhɪstəʊ'kemɪstrɪ]
美[ɪmjʊnoʊhɪstoʊ'kemɪstrɪ]
[词典]免疫组织化学;
[例句]Methods Transmission electron microscope and immunohistochemistry were used.
方法采用透射电镜和免疫组化法。