
Product Name | Bid BH3 - r8rrrrrrrr - GEDIIRNIARHLAQVGDSMDR |
Size | 0.5 mg |
Catalog # | AS-61715 |
US$ | $374 |
Purity | % Peak Area By HPLC ≥ 95% |
The Bid BH3 is a pro-apoptotic member of the "BH3-only" subset of BCL-2 family proteins that constitute a critical control point in apoptosis. r8BIDBH3 is lethal to human leukemia cell lines that expresse Bcl-2. The Bcl-2 antagonists may have the potential to be efficacious in cancer therapy. Poly-D-arginine (d-isomer as denoted by rrrrrrrr) is fused to the Bid BH3 peptide to facilitate cellular uptake of the peptide. | |
Detailed Information | ![]() |
Storage | -20°C |
References | Letai, A. J.Clin. Invest. 115, 2648 (2005); Mendoza, F. et al. Arch. Immunol. Ther. Exp. 53, 47 (2002). |
Molecular Weight | 3616.2 |
rrrrrrrr-GEDIIRNIARHLAQVGDSMDR | |
Sequence(Three-Letter Code) | H - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - D - Arg - Gly - Glu - Asp - Ile - Ile - Arg - Asn - Ile - Ala - Arg - His - Leu - Ala - Gln - Val - Gly - Asp - Ser - Met - Asp - Arg |
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英 [ˈpɒlɪmə(r)]
美 [ˈpɑ:lɪmə(r)]
n.
多聚物; [高分子] 聚合物;
[例句]The nature of the polymer is currently a trade secret.
这一聚合物的性质目前是个商业机密。
[其他]
复数:polymers
高分子化合物又称高分子(聚合物),高分子是由分子量很大的长链分子所组成,高分子的分子量从几千到几十万甚至几百万。而每个分子链都是由共价键联合的成百上千的一种或多种小分子构造而成。高分子的分类有多种,按来源可分为天然高分子、天然高分子衍生物、合成高分子三大类;根据用途则可分为合成树脂和塑料、合成橡胶、合成纤维等;按热行为可分为热塑性和热固性聚合物;按主链结构可分为碳链、杂链、和元素有机三类;另外根据工业产量和价格还可分为通用高分子、中间高分子、工程塑料以及特种高分子等等。
免疫组化多聚物法
immunohistochemistry
英[ɪmjʊnəʊhɪstəʊ'kemɪstrɪ]
美[ɪmjʊnoʊhɪstoʊ'kemɪstrɪ]
[词典]免疫组织化学;
[例句]Methods Transmission electron microscope and immunohistochemistry were used.
方法采用透射电镜和免疫组化法。
苏州高分子科学先进材料有限公司
polymer英[ˈpɒlɪmə(r)]美[ˈpɑ:lɪmə(r)]
n.多聚物; [高分子] 聚合物;
[例句]The nature of the polymer is currently a trade secret.
这一聚合物的性质目前是个商业机密。
[其他]复数:polymers
Author:AndrewJ.Hall,MilenaQuaglia,PanagiotisManesiotis,ErsiliaDeLorenzi,andBörjeSellergren
Resource:AnalyticalChemistry,2006,78(24):8362-8367.
Abstract:
Arangeof2-acrylamidopyridines,showingsubtledifferencesinsolutionbindingtowardcarboxylicacids,hasbeeninvestigatedasfunctionalmonomersinmolecularimprinting.ImprintingofN-Z-L-glutamicacidwithonesuchmonomerisshowntobeeffectiveinthecreationofamolecularlyimprintedpolymer(MIP)withrecognitionpropertiesforitstemplateandalsoforlargermoleculescontainingglutamicacidresidues.IncomparisontoaMIPpreparedviaamore"trADItional"approach,thenewpolymericreceptorsexhibitreducednonspecificbinding.Thenewreceptorsarecomparedwithpreviouslyreportedurea-basedreceptorstargetingtheglutamicacidresidueandreceptorstargetingthepteridinesubstructureoffolicacid.
PMID:17165828

