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NF-κBessentialmodulator(NEMO)isaregulatorysubunitwithinIκBkinase(IKK).IKKisalsocomposedoftwounrelatedcatalyticsubunitscalledIKKαandIKKβ.NEMOisadditionallyreferredtoasIKKγ,IKKAP1,orFIP-3.IKKisresponsIBLeforactivatingthetranscriptionfactor,NF-κB,whichisinvolvedinimmuneresponse.NEMOpreferstobindK63-linkedorlinearpolyubiquitinchains.
AdditionalInformation
ProductName: | GST-NEMO |
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AlsoKnownAs: | IKBKG;IP;IP1;IP2;FIP3;IPD2;NEMO;FIP-3;Fip3p;AMCBX1;ZC2HC9;IKK-gamma |
CatalogNo.: | I1500 |
Size: | 25µg |
MolecularWeight: | 48.2kDa |
Species: | Human |
Source: | Bacterialrecombinant |
Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
Concentration: | Seetubelabel |
QualityAssurance: | ~85%bySDS-PAGE,seedatasheetforgelimage |
Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
PDFDataSheet: | PDFDatasheet,MSDS |
NCBIRefSeq: | NM_001099857 |
Image(s): | N/A |
ShippingMethod: | Dryiceshipping |
References: | 1.RothwarfDM,etal.(1998)Nature395,297–300. 2.YamaokaS,etal.(1998)Cell93,1231–1240.3.GhoshS,KarinM(2002)Cell109Suppl,S81–96. |