Tocris代理，产品目录 Tocris Bioscience经销商/代理商,Tocris/BYK 204165/3734/10/10 mg,DNA聚合酶,核酸酶类,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/BYK 204165/3734/10/10 mg

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Tocris

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3734/10

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4000-520-616

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Description:SelectivePARP-1inhibitor

ChemicalName:4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivepoly(ADP-ribose)polymerase(PARP)-1inhibitor(pIC₅₀valuesare5.38and7.35forPARP-2andPARP-1respectively).

CompoundLibraries

BYK204165isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	252.27
Formula	C₁₅H₁₂N₂O₂
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	1104546-89-5
PubChemID	25113764
InChIKey	BTYSIDSTHDDAJW-LCYFTJDESA-N
Smiles	O=C(NC3=O)C1=CC=CC=C1/C3=C/C2=CC=CN2C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	25.23	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight252.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.96mL	19.82mL	39.64mL
5mM	0.79mL	3.96mL	7.93mL
10mM	0.4mL	1.98mL	3.96mL
50mM	0.08mL	0.4mL	0.79mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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