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Tocris/UPF 1069/3736/10/10 mg
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Tocris/UPF 1069/3736/10/10 mg
品牌 / 
Tocris
货号 / 
3736/10
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4000-520-616
Description:PARP-2inhibitor
ChemicalName:5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivepoly(ADP-ribose)polymerase(PARP)2inhibitor(IC50valuesare0.3and8.0μMforPARP-2andPARP-1respectively).

CompoundLibraries

UPF1069isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt279.29
FormulaC17H13NO3
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber1048371-03-4
PubChemID25015515
InChIKeyJJWMRRNGWSITSQ-UHFFFAOYSA-N
SmilesO=C2NC=CC1=C(OCC(C3=CC=CC=C3)=O)C=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO27.93100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight279.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.58mL17.9mL35.81mL
5mM0.72mL3.58mL7.16mL
10mM0.36mL1.79mL3.58mL
50mM0.07mL0.36mL0.72mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet