Tocris中国采购 Tocris Bioscience授权代理商，正品,Tocris/CC 0651/4503/10/10 mg,连接酶,核酸酶类,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/CC 0651/4503/10/10 mg

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Tocris

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4503/10

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Description:AllostericinhibitorofhCdc34

ChemicalName:(2R,3S,4S)-5-[4-(3,5-Dichlorophenyl)phenyl]-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AllostericinhibitorofhumanCdc34.InhibitshCdc34-mediatedubiquitinationofp27^Kip1(IC₅₀=1.72μM).ExhibitsselectivityforhCdc34overUba1,Ube2G1,UbcH7,UbcH5,Ube2N(Ubc13),Ube2R2,SMURF2,SspH1andRnf168.

TechnicalData

M.Wt	442.29
Formula	C₂₀H₂₁Cl₂NO₆
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1319207-44-7
PubChemID	53239927
InChIKey	NTCBTNCWNRCBGX-YTQUADARSA-N
Smiles	ClC1=CC(Cl)=CC(C2=CC=C(C[C@H](NC(COC)=O)[C@@H]([C@H](C(O)=O)O)O)C=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.NaOH	44.23	100
	DMSO	44.23	100
	ethanol	22.11	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight442.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.26mL	11.3mL	22.61mL
5mM	0.45mL	2.26mL	4.52mL
10mM	0.23mL	1.13mL	2.26mL
50mM	0.05mL	0.23mL	0.45mL

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