品牌试剂实验Tocris代理 Tocris多肽,Tocris/BPIPP/3635/50/50 mg,其它酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/BPIPP/3635/50/50 mg

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Tocris

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3635/50

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4000-520-616

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Description:Non-competitiveGCinhibitor.AlsoACinhibitor

ChemicalName:5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Non-competitiveguanylylcyclase(GC)andadenylylcyclase(AC)inhibitor.DownregulatescAMPandcGMPsynthesis,andsuppressescGMPaccumulationinavarietyofcelllines(IC₅₀=3.4-11.2μM).InhibitsGC-stimulatedCl^-transportinvitroandsuppressestoxin-inducedintestinalfluidaccumulationinvivo.

TechnicalData

M.Wt	450.28
Formula	C₂₂H₁₆BrN₃O₃
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	325746-94-9
PubChemID	4410990
InChIKey	QSZKQDDYOLAPII-UHFFFAOYSA-N
Smiles	O=C(C5=C4C=CC=C5)C2=C4NC(N1C)=C(C2C3=CC(Br)=CC=C3)C(N(C)C1=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	0.9	2

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight450.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.22mL	11.1mL	22.21mL
5mM	0.44mL	2.22mL	4.44mL
10mM	0.22mL	1.11mL	2.22mL
50mM	0.04mL	0.22mL	0.44mL

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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