Tocris公司代理生物计划 Tocris小分子,Tocris/FIPI/3600/10/10 mg,其它酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/FIPI/3600/10/10 mg

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Tocris

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3600/10

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4000-520-616

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Description:PhospholipaseDinhibitor

ChemicalName:N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethy]-5-fluoro-1H-indole-2-carboxamidehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentphosholipaseD(PLD)inhibitor(IC₅₀valuesare20and25nMforPLD₂andPLD₁respectively).AmelioratesPLD₂-drivensuppressionofmembranerufflingandcellspreADIng.Orallyavailable.

CompoundLibraries

FIPIisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	457.93
Formula	C₂₃H₂₄FN₅O₂.HCl
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	939055-18-2
PubChemID	90488864
InChIKey	BNMQCDOCYPGJJD-UHFFFAOYSA-N
Smiles	O=C(N2)N(C3CCN(CCNC(C4=CC5=C(C=CC(F)=C5)N4)=O)CC3)C1=C2C=CC=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	22.9	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight457.93.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.18mL	10.92mL	21.84mL
5mM	0.44mL	2.18mL	4.37mL
10mM	0.22mL	1.09mL	2.18mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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PreparingStockSolutions

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