Tocris配体 Tocris化合物筛选文库,Tocris/GSK J2/4688/50/50 mg,其它酶,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/GSK J2/4688/50/50 mg

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Tocris

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4688/50

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4000-520-616

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Description:InactiveisomerofGSKJ1(Cat.No.4593)

ChemicalName:N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanineethylester

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InactivecontrolofGSKJ1(CatNo.4593)(IC₅₀>100μMforinhibitionofJMJD3/UTX).Cellpermeableesterderivative,GSKJ5(Cat.No.4689),alsoavailable.

LicensingInformation

ThiscompoundissuppliedinconjunctionwiththeStructuralGenomicsConsortium.ForfurtherdetailsofGSKJ2,aninactiveisomerofGSKJ1,pleasevisittheGSKJ1probesummaryontheSGCwebsite.

CompoundLibraries

GSKJ2isalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	389.45
Formula	C₂₂H₂₃N₅O₂
Storage	DesiccateatRT
Purity	≥98%(HPLC)
CASNumber	1394854-52-4
PubChemID	73010924
InChIKey	LJIFOCRGDDQFJF-UHFFFAOYSA-N
Smiles	O=C(CCNC1=NC(C2=CC=CN=C2)=NC(N3CCC(C=CC=C4)=C4CC3)=C1)O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	19.47	50
	DMSO	38.94	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight389.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.57mL	12.84mL	25.68mL
5mM	0.51mL	2.57mL	5.14mL
10mM	0.26mL	1.28mL	2.57mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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