BiologicalActivity
Endogenouspeptideactivatorofintestinalguanylylcyclase;secretedmainlybythegastrointestinalmucosa.Regulateswaterandelectrolytetransportinintestinalandrenalepithelia.
TechnicalData
| M.Wt | 1458.65 |
| Formula | C58H87N15O21S4 |
| Sequence | PGTCEICAYAACTGC (Modifications:Cys-15=C-terminalOH,DisulfideBridgebetween4-2,7-5) |
| Storage | Desiccateat-20°C |
| CASNumber | 183200-12-6 |
| PubChemID | 90488722 |
| InChIKey | XPNQMTAYRNMRRD-RDJGHUJSSA-N |
| Smiles | [H]N1CCC[C@H]1C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC1=O)[C@@H](C)CC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1458.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.69mL | 3.43mL | 6.86mL |
| 5mM | 0.14mL | 0.69mL | 1.37mL |
| 10mM | 0.07mL | 0.34mL | 0.69mL |
| 50mM | 0.01mL | 0.07mL | 0.14mL |
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