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Description:InhibitorofclassIα-mannosidases
ChemicalName:(5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
InhibitorofclassIα-mannosidasesthatinhibitsglycoproteinprocessing.Inhibitshumanendoplasmicreticulumα-1,2-mannosidaseIandGolgiClassImannosidasesIA,IBandICwithKivaluesof130and23nMrespectively.
TechnicalData
M.Wt | 232.19 |
Formula | C8H12N2O6 |
Storage | Storeat-20°C |
CASNumber | 109944-15-2 |
PubChemID | 130611 |
InChIKey | OIURYJWYVIAOCW-PQMKYFCFSA-N |
Smiles | O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)N2[C@@]([H])1NC(C2=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
water | 2.32 | 10mMwithsonication |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight232.19.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.31mL | 21.53mL | 43.07mL |
5mM | 0.86mL | 4.31mL | 8.61mL |
10mM | 0.43mL | 2.15mL | 4.31mL |
50mM | 0.09mL | 0.43mL | 0.86mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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