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Tocris/ASP 9521/6084/50/50 mg
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Tocris/ASP 9521/6084/50/50 mg
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Tocris
货号 / 
6084/50
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4000-520-616
Description:Potent17β-hydroxysteroiddehydrogenasetype5inhibitor;orallybioavailable
ChemicalName:[4-(2-Hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)methanone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent17β-hydroxysteroiddehydrogenasetype5inhibitor(IC50=11-49nM).Suppressesandrostenedione-dependentprotein-specificantigen(PSA)productionandcellproliferationinLNCaPcellsinvitro.Orallybioavailable.

TechnicalData

M.Wt330.42
FormulaC19H26N2O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1126084-37-4
PubChemID25210792
InChIKeyOXSCPDKUZWPWFR-UHFFFAOYSA-N
SmilesO=C(N1CCC(CC1)CC(C)(O)C)C2=CC3=CC(OC)=CC=C3N2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO33.04100
ethanol33.04100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight330.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.03mL15.13mL30.26mL
5mM0.61mL3.03mL6.05mL
10mM0.3mL1.51mL3.03mL
50mM0.06mL0.3mL0.61mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet