BiologicalActivity
Orallyactiveα-glucosidaseIandIIandceramide-specificglycosyltransferaseinhibitor.Rescuestrafficking-deficientF508del-CFTRinhumanairwayepithelialcellsviainhibitionofERα-glucosidasesIandII.Alsohasbroadspectrumantiviralactivity.
TechnicalData
| M.Wt | 255.74 |
| Formula | C10H21NO4.HCl |
| Storage | Desiccateat-20°C |
| CASNumber | 210110-90-0 |
| PubChemID | 657399 |
| InChIKey | QPAFAUYWVZMWPR-ZSOUGHPYSA-N |
| Smiles | CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 19.18 | 75 | |
| water | 19.18 | 75 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight255.74.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.91mL | 19.55mL | 39.1mL |
| 5mM | 0.78mL | 3.91mL | 7.82mL |
| 10mM | 0.39mL | 1.96mL | 3.91mL |
| 50mM | 0.08mL | 0.39mL | 0.78mL |
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