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Description:LDHAinhibitor
ChemicalName:Methyl1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
LDHAinhibitor;reduceslactateproductioninHeLacells.InhibitscellgrowthofLPC006andPANC-1cellsinvitro.AlsoenhancestheantiproliferativeeffectsofGemcitABIne(Cat.No.3259)onLPC006andPANC-1cells.
CompoundLibraries
NHI2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 335.28 |
Formula | C17H12F3NO3 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 1269802-97-2 |
PubChemID | 51355147 |
InChIKey | YPPFWRWCZNXINO-UHFFFAOYSA-N |
Smiles | ON2C1=CC(C3=CC=CC=C3)=CC(C(F)(F)F)=C1C=C2C(OC)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 33.53 | 100 | |
ethanol | 33.53 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight335.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.98mL | 14.91mL | 29.83mL |
5mM | 0.6mL | 2.98mL | 5.97mL |
10mM | 0.3mL | 1.49mL | 2.98mL |
50mM | 0.06mL | 0.3mL | 0.6mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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