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Tocris/NHI 2/5363/50/50 mg
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Tocris/NHI 2/5363/50/50 mg
品牌 / 
Tocris
货号 / 
5363/50
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4000-520-616
Description:LDHAinhibitor
ChemicalName:Methyl1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

LDHAinhibitor;reduceslactateproductioninHeLacells.InhibitscellgrowthofLPC006andPANC-1cellsinvitro.AlsoenhancestheantiproliferativeeffectsofGemcitABIne(Cat.No.3259)onLPC006andPANC-1cells.

CompoundLibraries

NHI2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt335.28
FormulaC17H12F3NO3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1269802-97-2
PubChemID51355147
InChIKeyYPPFWRWCZNXINO-UHFFFAOYSA-N
SmilesON2C1=CC(C3=CC=CC=C3)=CC(C(F)(F)F)=C1C=C2C(OC)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO33.53100
ethanol33.53100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight335.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.98mL14.91mL29.83mL
5mM0.6mL2.98mL5.97mL
10mM0.3mL1.49mL2.98mL
50mM0.06mL0.3mL0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet