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Description:PDE4inhibitor.Moreactiveenantiomerofrolipram(Cat.No.0905)
ChemicalName:(4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
MoreactiveenantiomerofthePDE4inhibitorrolipram(Cat.No.0905);2-10-foldmorepotentthantheS-(+)enantiomer(Cat.No.1350).AlsoavailableaspartofthePhosphodiesteraseInhibitorTocriset™.
CompoundLibraries
(R)-(-)-RolipramisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 275.35 |
Formula | C16H21NO3 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 85416-75-7 |
PubChemID | 448055 |
InChIKey | HJORMJIFDVBMOB-LBPRGKRZSA-N |
Smiles | O=C1NC[C@@H](C2=CC(OC3CCCC3)=C(OC)C=C2)C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 27.54 | 100 | |
ethanol | 27.54 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight275.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.63mL | 18.16mL | 36.32mL |
5mM | 0.73mL | 3.63mL | 7.26mL |
10mM | 0.36mL | 1.82mL | 3.63mL |
50mM | 0.07mL | 0.36mL | 0.73mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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