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Description:Cystathioneγlyase(CSE)inhibitor
ChemicalName:(R)-2-Oxo-N-2-propyn-1-yl-4-thiazolidinecarboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Cystathioneγlyase(CSE)inhibitor(IC50=6.3μM).InhibitsH2SproductioninmouseaortahomogenatesandL-cysteine-inducedrelaxationofrataorticringsexvivo.
TechnicalData
M.Wt | 184.22 |
Formula | C7H8N2O2S |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
PubChemID | 124221753 |
InChIKey | MWEQVHWJNCRXGP-YFKPBYRVSA-N |
Smiles | O=C([C@@H]1CSC(N1)=O)NCC#C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 18.42 | 100 | |
ethanol | 9.21 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight184.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 5.43mL | 27.14mL | 54.28mL |
5mM | 1.09mL | 5.43mL | 10.86mL |
10mM | 0.54mL | 2.71mL | 5.43mL |
50mM | 0.11mL | 0.54mL | 1.09mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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