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Tocris/SPL 334/5809/10/10 mg

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Tocris

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5809/10

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4000-520-616

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Description:S-Nitrosoglutathionereductaseinhibitor

ChemicalName:4-[[2-[[(2-Cyanophenyl)methyl]thio]-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl]methyl]benzoicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

S-Nitrosoglutathionereductaseinhibitor.Preventsweightloss,andattenuateslunginflammationandfibrosisinableomycininjurymodelofinterstitiallungdiseaseinmice.

TechnicalData

M.Wt	433.5
Formula	C₂₂H₁₅N₃O₃S₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	688347-51-5
PubChemID	3651705
InChIKey	UWWSCLNCHCROLL-UHFFFAOYSA-N
Smiles	OC(C1=CC=C(C=C1)CN2C(C3=C(N=C2SCC4=C(C#N)C=CC=C4)C=CS3)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	43.35	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight433.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.31mL	11.53mL	23.07mL
5mM	0.46mL	2.31mL	4.61mL
10mM	0.23mL	1.15mL	2.31mL
50mM	0.05mL	0.23mL	0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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