BiologicalActivity
InhibitorofGLUT1;inhibitsglucoseuptakeinrenalcellcarcinoma(RCC)4cells.ActivitycausesnecroticcelldeathinvonHippel-Lindau(VHL)-deficientRCCcells.AlsoNAMPTinhibitor.Eliminateshumanpluripotentstemcellsfromculturewithlimitedtoxicitytowardsdifferentiatedcells.
CompoundLibraries
STF31isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 423.53 |
| Formula | C23H25N3O3S |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 724741-75-7 |
| PubChemID | 984333 |
| InChIKey | NGQPRVWTFNBUHA-UHFFFAOYSA-N |
| Smiles | O=C(NC2=CN=CC=C2)C1=CC=C(CNS(C3=CC=C(C(C)(C)C)C=C3)(=O)=O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 42.35 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight423.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.36mL | 11.81mL | 23.61mL |
| 5mM | 0.47mL | 2.36mL | 4.72mL |
| 10mM | 0.24mL | 1.18mL | 2.36mL |
| 50mM | 0.05mL | 0.24mL | 0.47mL |
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