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Tocris/Siguazodan/1148/10/10 mg

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Tocris

货号 /

1148/10

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4000-520-616

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Description:PDE3inhibitor

ChemicalName:N-Cyano-N'-methyl-N''-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]guanidine

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Phosphodiesteraseinhibitor,selectiveforPDE3(IC₅₀=117nM).

CompoundLibraries

SiguazodanisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	284.32
Formula	C₁₄H₁₆N₆O
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	115344-47-3
PubChemID	72124
InChIKey	NUHPODZZKHQQET-UHFFFAOYSA-N
Smiles	CNC(NC#N)=N/C1=CC=C(C=C1)C1=NNC(=O)CC1C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto100mMinDMSO

Solubility

Solubleto100mMinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight284.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.52mL	17.59mL	35.17mL
5mM	0.7mL	3.52mL	7.03mL
10mM	0.35mL	1.76mL	3.52mL
50mM	0.07mL	0.35mL	0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

DilutionCalculator

ProductDatasheets