Tocris美元价/进货价 TOCRIS 4372-10MG,Tocris/TFC 007/5108/50/50 mg,其它酶,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/TFC 007/5108/50/50 mg

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Tocris

货号 /

5108/50

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4000-520-616

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Description:PotenthematopoieticprostaglandinDsynthase(H-PGDS)inhibitor

ChemicalName:N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotenthematopoieticprostaglandinDsynthase(H-PGDS)inhibitor(IC₅₀=83nM).InhibitsPGD₂productionandlatephasenasalblockageinananimalmodelofallergicrhinitis.ExhibitsnegligIBLeeffectsonCOX-1,COX-2,5-LOX,LTC₄synthase,TXA₂synthaseandmicrosomalprostaglandinE₂synthase.

CompoundLibraries

TFC007isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	487.55
Formula	C₂₇H₂₉N₅O₄
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	927878-49-7
PubChemID	16040067
InChIKey	NLSSUSRERAMBTA-UHFFFAOYSA-N
Smiles	O=C(C2CCN(C3=CC=C(NC(C4=CN=C(OC5=CC=CC=C5)N=C4)=O)C=C3)CC2)N1CCOCC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	48.76	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight487.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.05mL	10.26mL	20.51mL
5mM	0.41mL	2.05mL	4.1mL
10mM	0.21mL	1.03mL	2.05mL
50mM	0.04mL	0.21mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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