BiologicalActivity
Non-competitiveMAGLinhibitor.ExhibitsselectivityforMAGLoverFAAH,diacylglycerollipaseandCOX2.Blocks2-AGhydrolysisinratbrainslices.Enhancesstress-inducedanalgesiainrats.
TechnicalData
| M.Wt | 295.38 |
| Formula | C19H21NO2 |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 565460-15-3 |
| PubChemID | 10979337 |
| InChIKey | HHVUFQYJOSFTEH-UHFFFAOYSA-N |
| Smiles | O=C(OC1CCCCC1)NC2=CC=CC(C3=CC=CC=C3)=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.54 | 100 | |
| ethanol | 29.54 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight295.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.39mL | 16.93mL | 33.85mL |
| 5mM | 0.68mL | 3.39mL | 6.77mL |
| 10mM | 0.34mL | 1.69mL | 3.39mL |
| 50mM | 0.07mL | 0.34mL | 0.68mL |
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