
Background
Chloroquinephosphateisa4-aminoquinolineanti-malarialandanti-rheumatoidagent,alsoactingasanATMactivator.Inhibitsautophagyinavarietyofcelllines1.Inducescelldeathinbreastcancercelllinesanddisplaysantitumorandantimetastaticactivityinmousemodelsofbreastcancer2.EliminatescancerstemcellsviaderegulationofJak2andDNMT13.DisplayssynergywhencombinedwiththeRafinhibitor,vemurafenib,inbraintumors4.Cellpermeableandactiveinvivo.
Application
AutophagyInhibitor
ProductInformation
Purity: >98.0%byTLC
MW: 515.9
Formula: C18H26ClN3.2H3O4P
CASNo. 50-63-5
PhysicalState: Lyophilizedwhitepowder
Amount: 5mg,25mg,50mg
Solubility: 25mg/mLinwater
Storage: Storedesiccatedassuppliedatambienttemperatureforupto2years.Storesolutionsat-20°Cforupto3months.
References
1.HBFrieboesetal.JOP201415:189
2.PDJiangetal.Biomed.Pharmacother.201064:609
3.DSChoietal.StemCells201432:2309
4.JMMulcahyLevyetal.CancerDiscov.20144:773
Documents
ebiomall.com






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明白了么,少年?
反应体系如下:
plasmid10ul
10xKbuffer5ul
KpnI1ul
BamHI1ul注意千万不可多加总酶量必须<4%
ddH20upto50ul
总体积改变加酶量按比例改变.
如果能分解,那小肠液中的消化酶如何大量共存,如果不能
那它如何识别其他蛋白质物质是不是消化酶?

