
UBE2FisanE2conjugationenzymethatisinvolvedintheubiquitylationoftargetsubstrates,alongwithE1andE3enzymes.UBE2FmediatesthetransferofNEDD8fromNEDD8-activatingenzymeE1(UBA3-NAE1complex)toasubstrateprotein.ThisE2enzymehasbeenshowntoassociatewiththebothNEDD8E3ligaseandRBX2,yetdisplaysdifferenttargetcullinspecificitiesthanasimilarUBE2M/RBX1E2/E3complex.
Info
Amount | 0.8nmol |
State | Liquid |
MolecularWeight | 21,077Da |
Source | HumanRecombinant |
FusionTag | None |
AccessionNumber | Q969M7 |
AlternateNames | Nedd8carrierprotein,Nedd8conjugatingenzyme2(NCE2) |
Storage | -80°C,avoidfreeze/thawcycles |
StABIlity | 1yearunderrecommendedstorageconditions |
RecommendedUse | Enzymeconcentrationof100nM–1mMisrecommendedfor invitro conjugation. |
Applications
- IdentifycognateE2/E3pairs
- Characterizeupregulation/downregulationofE2enzymes
- Buildpoly-ubiquitinchains
- CharacterizeubiquitinchainspecificityofE2enzymes
- AnalyzeexpressionofE2enzymes
Benefits
- Untagged(native)E2conjugationenzyme
Documents
ebiomall.com






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DNMT3a,Dnmt3a,DNMT3A三者有何区别呢,在大鼠或者小鼠身上,用来指酶或者基因时,应该如何表达呢?谢谢
请教各位老师,
文献中检测细胞的活性有的用“NADPHdehydrogenase(NADPH脱氢酶)”有的用“NADPHdiaphorase(NADPH黄递酶)”
它们是同一种酶吗?它们的功能是什么?检测它们的活性是否能够评估细胞的活性。
不胜感激
明白了么,少年?

