Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Target Species:
Human
Product Type:
Recombinant Proteins
Description:
Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human 4-1BB, His Tag at 100 ng/mL (100 ul/well),can bind Human 4-1BB Ligand, Fc Tag with a linear of 0.1-2.5 ng/mL (Routinely tested).
Source Species: HEK293 cells
Fusion Tag: Fc Tag
Sequence: Ala 50 - Glu 254
Purity: >95% as determined by SDS-PAGE.Endotoxin level is less than 1.0 EU per ug by the LAL method.
Supplier:
ProSci
Product Category:
Immunity and Infection > Allergy & Immunology
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
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