
Product information | Protocols | References | Technical support | Reviews |
Product name | GABA antibody - mouse mAb |
Synonyms | Anti-g-Aminobutyric acid antibody Anti-gamma-Aminobutyric acid antibody |
Immunogen | Conjugated GABA |
Specificity | When tested in competitive ELISA, the anti-conjugated GABA antibody didnot show any significant cross reactivity with gamma-Aminobutyric acidanalogs, including beta-Alanine and L.Glutamate. |
Volume | 50µL |
Lot number | 170307 |
Storage
Form | Liquid |
Purity | Purified IgG1 (lambda) |
Storage | Store at +4°C for short term (1-2 months). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles. |
Material safety datasheet | Download MSDS |
Protocols
IF - Cell cultures, Whole mounts, Tissue sections
Dilute antibody with the antibody diluent provided in the STAINperfect immunostaining kit A. Use at 1/250 -1/1000 dilution. Follow the STAINperfect protocol suited to your sample | |
Comments | Optimal working dilutions must be determined by the end-user |
Restrictions | For research use only |
Full protocol | Download STAINperfect protocol for GABA staining |
Protocols-at-a-glance |
![]() | ![]() | ![]() | ![]() |
Complete Instructions for Use | Protocol-at-a-glance for cell cultures | Protocol-at-a-glance for whole mounts | Protocol-at-a-glance for tissue sections |
Enregistrer
TopReferences
Antibody not yet cited. Submit an article and get a 10% discount.
Selected articles on GABA:
- LiuX, Wang Q, Haydar TF, Bordey A. Nonsynaptic GABA signaling in postnatalsubventricular zone controls proliferation of GFAP-expressingprogenitors. Nat Neurosci. 2005 Sep;8(9):1179-87. Epub 2005 Aug 14.
- LawrenceJJ. Cholinergic control of GABA release: emerging parallels betweenneocortex and hippocampus. Trends Neurosci. 2008 Jul;31(7):317-27. doi:10.1016/j.tins.2008.03.008. Epub 2008 Jun 13.
- BaulacS, Huberfeld G, Gourfinkel-An I, Mitropoulou G, Beranger A, Prud"hommeJF, Baulac M, Brice A, Bruzzone R, LeGuern E. First genetic evidence ofGABA(A) receptor dysfunction in epilepsy: a mutation in thegamma2-subunit gene. Nat Genet. 2001 May;28(1):46-8.
Technical SupportSubmit a question
No technical question yet. Be the first to ask!TopReviewsSubmit your review
No reviews yet. Thanks for rating this product.Topebiomall.com






>
>
>
>
>
>
>
>
>
>
>
>
三种酶分别反映肝脏的不同病理过程:
ALT增高往往说明肝实质细胞的损伤;GGTP增高可以说明胆汁淤积和对肝的“诱导作用”;测定CHE可以检查肝脏的蛋白合成功能。
它只是一个检验科的检验设备,用来化验血液、尿液中的成分浓度,医生据此来诊断疾病,可以查很多项目,如乙肝五项等等,不能直接检查什么疾病。
看有关产前诊断的一个资料,提到:“凡是酶活性能在成纤维细胞中表达均可用绒毛或羊水细胞的酶活性测定进行产前诊断,如溶酶体贮积症。”
不太理解,为什么成纤维细胞中表达的酶就能在绒毛或羊水细胞中测出来呢?绒毛的细胞跟成纤维细胞没什么直接关系吧?或者是因为成纤维细胞脱落到羊水中,破裂,然后就可以检测了?
求各位解答,谢谢。
转换酶中的一类。催化氨基酸和a-氧代酸(a-酮酸
)或醛酸之间的氨基转换反应,生成与原来的a-氧代酸或醛酸相应的a-氨基酸或ω-
氨基酸,原来氨基酸转变成相应的氧代酸。转氨酶催化的反应都是可逆的。转氨酶可按底物的不同分成3大类。L-a-氨基酸(酮酸转氨酶) 、ω-
氨基酸(酮酸转氨酶)和D-氨基酸转氨酶。转氨酶的辅基是磷酸吡哆醛或磷酸吡哆胺,两者在转氨基反应中可互相变换。
转氨酶参与氨基酸的分解和合成。氨基酸转氨后生成的酮酸或醛酸可经氧化分解而供能,也可转变成糖类或脂肪酸。相反,酮酸或醛酸也可经转氨酶的作用而生成非必需氨基酸。某些氨基酸之间的互变也有转氨酶参与。在高等动物各组织中,活力最高的转氨酶是谷氨酸
: 草酰乙酸转氨酶( GOT )和谷氨酸:丙酮酸转氨酶(GPT)。
转氨酶是人体代谢过程中必不可少的“催化剂”,主要存在于肝细胞内。当肝细胞发生炎症、坏死、中毒等,造成肝细胞受损时,转氨酶便会释放到血液里,使血清转氨酶升高。
通常,体检中主要检查的转氨酶有丙氨酸转氨酶(ALT,俗称谷丙转氨酶)和天门冬氨酸转氨酶(AST,俗称谷草转氨酶),其中尤以前者(ALT)最为常用。1%的肝脏细胞损害,可以使血中ALT的浓度增加1倍。因此,ALT水平可以比较敏感地监测到肝脏是否受到损害。
~如果你认可我的回答,请及时点击【采纳为满意回答】按钮~ ~手机提问者在客户端右上角评价点“满意”即可。
~你的采纳是我前进的动力~~ ~如还有新的问题,请另外向我求助,答题不易,敬请谅解~~

