
- CID 2011756
- CID 755673
- CRT 0066101
kb NB 142-70Inhibitor of protein kinase D,selective |
Sample solution is provided at 25 µL, 10mM.
































Quality Control & MSDS
- View current batch:
- Purity = 98.21%
- COA (Certificate Of Analysis)
- HPLC
- NMR (Nuclear Magnetic Resonance)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure


kb NB 142-70 Dilution Calculator
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kb NB 142-70 Molarity Calculator
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Cas No. | 1233533-04-4 | SDF | Download SDF |
Chemical Name | 9-hydroxy-3,4-dihydro-2H-[1]benzothiolo[2,3-f][1,4]thiazepin-5-one | ||
Canonical SMILES | C1CSC2=C(C(=O)N1)SC3=C2C=C(C=C3)O | ||
Formula | C11H9NO2S2 | M.Wt | 251.32 |
Solubility | ≥12.9 mg/mL in DMSO, ≥8.05 mg/mL in EtOH with ultrasonic and warming, <2.71 mg/ml="" in="" h2o="">2.71> | Storage | Store at -20°C |
Physical Appearance | A solid | Shipping Condition | Evaluation sample solution : ship with blue ice.All other available size:ship with RT , or blue ice upon request |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
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我理解就是一个是包裹,一个是镶嵌
结合物垫在层析时荧光微球在T线前面凝集的现象怎么解决呢,结合物垫增加了吐温和糖的含量还是有这种现象的
1、该制剂为肌肉注射;
2、制备该微球过程中用到了二氯甲烷、乙醇、正庚烷、二甲基硅油。国家药典有机溶剂残留规定:二氯甲烷残留限度为0.06%;乙醇残留限度为0.5%;正庚烷残留限度0.5%;二甲基硅油药典中还为収载。目前自制微球的二氯甲烷残留约0.2%左右,正庚烷残留1.0%左右,乙醇残留0.3%左右,二甲基硅油暂未检测。很明显:二氯甲烷和正庚烷超标。后来测了一下原研制剂的有机溶剂残留:二氯甲烷残留约0.1%左右,正庚烷残留1.5%左右,乙醇残留0.2%左右。本人也制剂新手,请各位大神帮帮忙,积极发言。我这个长效缓释PLGA微球制剂中有机溶剂残留限应该定多少合适,我后期优化工艺时对上述有机残留应该控制到多少一下合适。

