BiologicalActivity
Water-solublecarbonmonoxide-releasingmolecule.Suppressesthrombin-inducednitritereleaseinBV-2microglia.Protectsisolatedratsheartsfromreperfusiondamageinvitroandiscardioprotectiveinaratmyocardialinfarctionmodelinvivo.Alsoprolongssurvivaloftransplantedheartsinmice.Exhibitsanti-inflammatoryandvasorelaxanteffects.
TechnicalData
| M.Wt | 294.61 |
| Formula | C5H4ClNO5Ru |
| Storage | Storeat-20°C |
| CASNumber | 475473-26-8 |
| PubChemID | 9817618 |
| InChIKey | BICHHHDSEZXKNN-UHFFFAOYSA-L |
| Smiles | O=C1[O-][Ru+2]([Cl-])([C]=O)([C]=O)([C]=O)[NH2]C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 29.46 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight294.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.39mL | 16.97mL | 33.94mL |
| 5mM | 0.68mL | 3.39mL | 6.79mL |
| 10mM | 0.34mL | 1.7mL | 3.39mL |
| 50mM | 0.07mL | 0.34mL | 0.68mL |
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