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Reaction Biology/HPA (Hexyl-4-pentynoic acid)/EI-HDC-004
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4000-520-616
| Hexyl-4-pentynoic acid |
2-(2-propynyl)octanoic acid(racemic); HPA
Hexyl-4-pentynoic acid is a valproic acid analog. Histone deacetylase(HDAC) inhibitor, IC50=13 mM1.More potent and robust than valproic acid at inducing histone hyperacetylation(600% at 50 mM), HSP70 induction and protection againstglutamate excitotoxicity in cultured neurons. Cell permeable.
Physical Properties: colorless oil
MW=182.3 C11H18O2
Analysis: >97% (TLC); NMR conforms
Solubilization: May be dissolved in DMSO (25mg/ml); or Ethanol (25 mg/ml)
Storage:Store as supplied at ambient temperature for up to 2 years. Storesolutions at -20°C for up to 3 months.
Amount: 10mg我要提问
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